Olli Matilainen

Etusivu / Henkilöstö / Olli Matilainen

Päivitetty 03.12.2025

Henkilökunta

Olli Matilainen

T&K Ohjelmajohtaja

Tulevaisuuskestävä terveys ja hyvinvointi innovaatiokeskittymä

Ota yhteyttä

Puhelin:

+358 40 756 6223

Sähköposti:

Olli.Matilainen@metropolia.fi

Postiosoite:

PL 4000, 00079 Metropolia

Kampus:

Myllypurontie 1, 00920 Helsinki

Näytä kartalla

Verkostoidu:

Osaaminen

Kielitaito

Julkaisut

Neopterin extends C. elegans lifespan in an ATFS-1-dependent manner; Pitkänen M, Monteuuis G, Jackson CB, Matilainen O*; microPublicationBiology. 2025 *corresponding author
Milk Fat Globule Membrane-Containing Protein Powder Promotes Fitness in Caenorhabditis elegans; Pitkänen M, Matilainen O*; Nutrients. 2024 *corresponding author
Loss of the histone chaperone UNC-85/ASF1 inhibits the epigenome-mediated longevity and modulates the activity of one-carbon metabolism; Shrestha B, Nieminen AI,…

Neopterin extends C. elegans lifespan in an ATFS-1-dependent manner; Pitkänen M, Monteuuis G, Jackson CB, Matilainen O*; microPublicationBiology. 2025 *corresponding author
Milk Fat Globule Membrane-Containing Protein Powder Promotes Fitness in Caenorhabditis elegans; Pitkänen M, Matilainen O*; Nutrients. 2024 *corresponding author
Loss of the histone chaperone UNC-85/ASF1 inhibits the epigenome-mediated longevity and modulates the activity of one-carbon metabolism; Shrestha B, Nieminen AI, Matilainen O*; Cell Stress and Chaperones. 2024 *corresponding author
Folate receptor overexpression induces toxicity in a diet-dependent manner in C. elegans; Shrestha B, Tallila M, Matilainen O*; Scientific Reports. 2024 *corresponding author
Loss of muscleblind splicing factor shortens Caenorhabditis elegans lifespan by reducing the activity of p38 MAPK/PMK-1 and transcription factors ATF-7 and Nrf/SKN-1; Matilainen O, Ribeiro ARS, Verbeeren J, Cetinbas M, Sood H, Sadreyev RI, Garcia SMDA.; Genetics. 2021
The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress; Matilainen O, Bou Sleiman MS, Quirós PM, Garcia SM, Auwerx J.; Nature Communications. 2017
Mitochondria and Epigenetics - Crosstalk in Homeostasis and Stress; Matilainen O*, Quirós PM*, Auwerx J.; Trends in Cell Biology. 2017 (Review) *equal contribution
Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4; Matilainen O, Arpalahti L, Rantanen V, Hautaniemi S, Holmberg CI; Cell Reports. 2013
A photoconvertible reporter of the ubiquitin-proteasome system in vivo; Hamer G*, Matilainen O*, Holmberg CI; Nature Methods. 2010 *equal contribution
Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity; Li X, Matilainen O, Jin C, Glover-Cutter KM, Holmberg CI, Blackwell TK; PLoS Genetics. 2011
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity; Merkwirth C*, Jovaisaite V*, Durieux J, Matilainen O, Jordan SD, Quiros PM, Steffen KK, Williams EG, Mouchiroud L, Tronnes SU, Murillo V, Wolff SC, Shaw RJ, Auwerx J, Dillin A.; Cell. 2016 *equal contribution
De novo NAD+ synthesis enhances mitochondrial function and improves health; Katsyuba E, Mottis A, Zietak M, De Franco F, van der Velpen V, Gariani K, Ryu D, Cialabrini L, Matilainen O, Liscio P, Giacchè N, Stokar-Regenscheit N, Legouis D, de Seigneux S, Ivanisevic J, Raffaelli N, Schoonjans K, Pellicciari R, Auwerx J.; Nature. 2018
Proteasome activity influences UV-mediated subnuclear localization changes of NPM; Moore HM, Bai B, Matilainen O, Colis L, Peltonen K, Laiho M.; PLoS One. 2013
Tissue-specific effects of temperature on proteasome function; Pispa J, Matilainen O, Holmberg CI.;Cell Stress Chaperones 2020
Anesthetic-like effects of ketamine in C. elegans; Seppälä K, Reigada I, Matilainen O, Rantamäki T, Hanski L.; Neuroscience 2025
Suppression of RNAi by dsRNA-degrading RNaseIII enzymes of viruses in animals and plants; Weinheimer I, Jiu Y, Rajamäki ML, Matilainen O, Kallijärvi J, Cuellar WJ, Lu R, Saarma M, Holmberg CI, Jäntti J, Valkonen JP.; PLoS Pathology 2015
Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1; Arczewska KD, Tomazella GG, Lindvall JM, Kassahun H, Maglioni S, Torgovnick A, Henriksson J, Matilainen O, Marquis BJ, Nelson BC, Jaruga P, Babaie E, Holmberg CI, Bürglin TR, Ventura N, Thiede B, Nilsen H.; Nucleic Acids Research 2013

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